Tissue augmentation

There are many applications for tissue augmentation techniques ranging from smoothing wrinkles, smoothing indentations left after trauma or plastic and reconstructive surgery, to relieving stress incontinence.

The easiest technique is to inject a material into the site requiring augmentation. Collagen is commonly used however it is not natural to humans and cannot be used for people allergic to it. Prior to injection, a sensitivity test needs to be carried out. Collagen has a another disadvantage in that it is resorbed over time and injections need to be repeated. Collagen sets up an inflammatory reaction and so never becomes a part of the healthy tissue.

For treating wrinkles, Botox is commonly used. This poison paralyses the muscles that cause creasing and of course affects the facial expresssion, giving a "Botox look". After the effect wears off a re-injection is needed.

If a natural look is desired, wrinkles can be smoothed permanently by augmenting the tissue under the wrinkle by injecting Coaptite.

Tissue augmentation by filling indentations after surgery and trauma with Coaptite facilitates reconstructive surgery.

Coaptite comprises synthetic calcium hydroxylapatite spheres. CaHA is the major constituent of bone and so is natural to the body. In soft tissue it is totally inert and tissue grows up to and onto the surfaces forming a soft and pliable tissue and Coaptite matrix. Eventually the Coaptite spheres are metabolised and replaced with healthy tissue - there is no loss of augmentation.

After the injection there is no indication that the indentations have been treated.The augmented tissue looks and feels completely normal.

 

COAPTITE FN

an easy-to-inject, biocompatible and tissue friendly augmenting product

Coaptite FN comprises smooth 30 micron spheres of synthetic calcium hydroxylapatite suspended in a mainly glycerine and water gel with a chemically-modified naturally occuring polysaccharide sodium carboxymethylcellulose as support.

CaHA is natural to the body and is inert in soft tissue. Neither the CaHA nor the gel cause tissue reaction or inflammation. There is no burning sensation when Coaptite is injected. The smooth 30 micron spheres are densely distributed in the gel so less material is needed for bulking.

The result is a permanent tissue augmentation that feels and looks as if no foreign material was used. It is ideal for applications ranging from the smoothing of facial lines to reconstruction after surgery or trauma.

                                                                                    

The patented carrier gel remains in situ until tissue grows in to take its place. Healthy
tissue grows through the deposit and against
the particles to form a tissue and Coaptite
matrix which remains soft and pliable.

                                                                                       

The deposit remains localised and stationary                within the injection site. There is no migration nor resorption.

                                                                                                                        

Soft and pliable tissue and Coaptite explant                    
after 12 months

 

 

 

The three slides are from dog tissue explanted 12 months after Coaptite injection.




Coaptite ™. ......The only solution to combine so many benefits.

  • Neither Coaptite nor the carrier gel cause tissue reaction and no inflammation occurs.
  • No capsule is formed around the implant.
  • Healthy tissue grows without change against and through the smooth CaHA spheres to form a soft and pliable tissue and Coaptite matrix.
  • There is no migration and no resorption.
  • The 30 micron spheres are smooth and densely packed in the carrier gel so that on average only 2.5ml of material is needed for stress incontinence.
  • Coaptite flows smoothly through the 21 guage needle with finger pressure control.
  • Three year results are excellent and show the improvement persisting.
  • Radiopaque
  • No sensitivity testing required. No special storage required.

Needle size: 27 guage                Supplied in 1cc syringes.

 

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